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The article specifically warns against assuming symptoms will resolve the moment the drug wears off, and says persistent or worsening symptoms belong in front of your provider
Two of the most promising options on the market today are Tirzepatide and Semaglutide
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In a trial of 1,961 adults conducted over 68 weeks, only 4.5% of those taking semaglutide discontinued the medications due to side effects, so both medications are safe for use, including in the long term
The Harrells C-statistic (area under the curve [AUC]) was used to evaluate the applicability of the CV risk prediction model to the semaglutide data (overall, efficacy trials alone, CVOTs alone), with values of 1.0 indicating a perfect predictive performance, 0.91.0 indicating an excellent performance, 0.80.9 indicating a good performance and 0.70.8 indicating a fair performance [32]
Some of the most common side effects in clinical trials included nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion (dyspepsia), and stomach (abdominal) pain
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