The microvascular risk equations were developed from US [26] and UK [27] populations, macrovascular risk equations were developed from a Swedish population [30], and mortality risk equations were developed from a UK population [29]
Looking Back on GLP-1 RAs Originally discovered in the saliva of the Gila monster, exenatide a GLP-1 RA was approved as a twice-daily injection by the FDA in 2005 for adults with type 2 diabetes
Baseline TSH and free T4 allow providers to monitor for changes during therapy, regardless of personal history
Potential adverse effects relevant to reproductive health Reported, as well as theoretically plausible, side effects include immune reactions, changed gut motility, and tissue growth
Key Takeaways: Ozempic and Pregnancy Ozempic is NOT safe during pregnancy and should not be used by pregnant women Stop Ozempic at least 2 months (8 weeks) before attempting conception Animal studies show potential risks to fetal development Insufficient human data exists to determine pregnancy safety If you become pregnant on Ozempic, stop immediately and contact your provider Use effective contraception while taking Ozempic if you dont want to become pregnant Breastfeeding safety is unknown
95% CI, 13.3 to 5.1 kg