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J Cell Biochem 104:13561363 Kawanishi N, Sugimoto T, Shibata J, Nakamura K, Masutani K, Ikuta M, Hirai H (2006) Structure-based drug design of a highly potent CDK1, 2, 4, 6 inhibitor with novel macrocyclic quinoxalin-2-one structure
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MHRA approval for cardiovascular risk reduction Based on the SELECT trial results, the MHRA approved Wegovy for cardiovascular risk reduction in July 2024
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There were no unexpected safety findings at the Phase 2 stage that would fundamentally alter the risk-benefit profile expected for this class
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