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3 Despite this limited direct action on the brain, semaglutide remains highly effective in reducing food intake and body weight, likely due to its peripheral actions and indirect influence on brain pathways
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However, the frequency of dulaglutide-related GI side effects dropped off markedly after the first 4-8 weeks, the side effects were mostly mild to moderate in nature, and very few patients dropped out of the study due to GI symptoms, according to Dr
Brekke MK, Northcote K, Temple WE
