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SARS-CoV-2 encodes ORF9b, a small accessory protein that localizes to mitochondria, interacts with translocase of the outer membrane (TOM70), and impedes MAVS-dependent signaling (Gao et al., 2021
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Nevertheless, conflicting views persist regarding the precise mechanistic pathways driving liver injury, with earlier reports emphasizing apoptosis, caspase-independent cell death, the ubiquitin-proteasome system, or ROS involvement [54]
Why purity matters for glutathione Glutathione oxidises readily to its disulfide form (GSSG) on exposure to air
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