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Evidence-based dietary choices, lifestyle modifications, and behavioural strategies can support natural GLP-1 secretion, offering a foundation for long-term metabolic health without medication

423 Pharmacological and herbal interventions Although lifestyle interventions can alleviate the symptoms of UC patients in the early stage, symptoms in the later stage cannot be treated by simple lifestyle interventions alone

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A comprehensive medical history is essential to identify contraindications, including personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, as GLP-1 agonists carry a boxed warning regarding thyroid C-cell tumors observed in rodent studies

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