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Hyperkalemia stimulates aldosterone production and aldosterone, in turn, enhances sodium and water reabsorption in exchange for potassium excretion in the distal tubule and collecting duct of the kidney

Three diabetes incretin medications are now approved for pediatric use starting at age 10 (see cheat sheet), and two incretin-based weight management medications are approved for children aged 12 and older

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Its label also includes cardiovascular risk reduction for certain adults, and it recently added an indication for adults with noncirrhotic MASH (metabolic dysfunction-associated steatohepatitis) and moderate to advanced fibrosis