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The ominous octet, which includes 8 key pathophysiologic defects found to be present in T2D, is illustrated in Figure 1
It makes the brain feel fullness while eating quicker, decreases spikes in hunger-signalling hormones, reduces cravings for sugary and high-carbohydrate foods, and slows digestion
Semaglutide vials need to be kept at a specific temperature to stay effective
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While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine
Ensure the injection site is clean and disinfected
