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5-Amino-1MQ inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that consumes NAD+ the coenzyme required for mitochondrial respiration and sirtuin activation

Also, high-dose B12 has been linked to acneiform eruptions in some case reports and reviews (Bahbouhi et al., 2023) as described in the PubMed record

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Vitamin B12 deficiency occurs when a person has insufficient vitamin B12

B complex supplements play a crucial role in maintaining optimum health by aiding in the conversion of food into energy