References & Sources SURPASS-2 Trial (N Engl J Med) SURMOUNT-1 Trial (N Engl J Med) SELECT Trial Semaglutide CV Outcomes (N Engl J Med) SUMMIT Trial Tirzepatide HFpEF (N Engl J Med) Eli Lilly SURPASS-2 Results (Press Release) Eli Lilly SURMOUNT-1 Results (Press Release) ADA SURPASS Data Presentation SUMMIT Trial ACC Summary SELECT Trial ACC Summary Disclaimer: This information is intended for general knowledge and informational purposes only and does not constitute medical advice
however, our exploratory comparison showed no difference in weight loss response to semaglutide
For instance, in the pivotal SURPASS-2 trial, patients receiving the highest tirzepatide dose (15 mg) achieved a mean body weight reduction of 11.2 kg, nearly twice that observed with semaglutide 1 mg (5.7 kg) (19)
The dedicated KLOW dosing page and GLOW dosing page cover operational details after that choice is made
Taking these two medications together might make these side effects worse
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