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doi: 10.1007/s40620-020-00789-y 21 FitzGeraldG

"We don't really know why some people only lose 5% where some people are super responders and losing 30% of their body weight." Kushner thinks of the result as a kind of new settling point the medication helps establish, though why it lands so much lower for some people isn't well understood

Brighten: Mm hmm

The drugs mimic naturally-occurring hormones which are released from the gut after meals

Lipedema involves abnormal fat deposition, typically in the legs and arms, that does not respond well to calorie restriction alone