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Focus on trends and wellbeing over months, not week-to-week scale fluctuations
Based on current information, there is no indication that using both treatments increases the risk or severity of side effects from either medication, though direct clinical studies on concurrent use are limited
For some individuals, these side effects can be challenging to manage, especially during the initial titration phase
doi: 10.3390/md17090518 148
A 28-year-old athlete with a grade II patellar tendinopathy and excellent sleep and nutrition may report dramatically different outcomes than a 55-year-old recreational runner with the same diagnosis and chronic sleep deprivation
In addition, this meta-analysis included few trials and had a low sample size and a high risk of bias
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