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The more practical question is whether peptides can complement existing therapies and potentially allow reduction of treatments that cause long-term side effects

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Trends Biochem Sci 41:10121021 Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT (2013) NLRP3 is activated in Alzheimers disease and contributes to pathology in APP/PS1 mice

In the current study, we found that the baseline level of the protein-bound form of glutathione significantly decreased after an overnight fast following 4 months of glutathione administration, especially in ALT responders

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