Indeed, melatonin was shown to reduce ROS and increase GSH levels in the colon, liver, ileum, and lung in irradiated rats long before ferroptosis was initially described [48]
References 1 AgarwalA
Immunoprecipitated and input DNA samples were analyzed by RT-qPCR on the Roche LightCycler 480 II Real-Time System
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Nonenzymatic lysine d-lactylation induced by glyoxalase II substrate SLG dampens inflammatory immune responses