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Patients should contact their GP within 24 to 48 hours if they experience persistent thirst that does not improve with increased fluid intake, particularly if accompanied by frequent urination, unexplained weight loss, or fatigue

Clinical trials of sodiumglucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists have shown beneficial effects of these agents on kidney outcomes in patients with type 2 diabetes mellitus

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Additionally, seek advice if you notice confirmed hypoglycaemia (blood glucose below 4.0 mmol/L) on multiple occasions, particularly if you are not taking sulphonylureas or insulin, or if you experience symptoms of dehydration such as reduced urine output, dark urine, extreme thirst, or confusion

Rx only References Bohmer, T., Rydning, A

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