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In August 2025, Wegovy was FDA-approved for the treatment of MASH in adults with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) based on results of the ESSENCE trial KNEE OSTEOARTHRITIS (OA) Knee osteoarthritis (OA) is caused and worsened by obesity, as both mechanical stress and obesity-induced inflammation accelerate joint destruction

Limiting screen time before bed to encourage better melatonin production

Do not estimate

For instance, individuals with a personal or family history of medullary thyroid carcinoma (MTC) or a condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should steer clear of this medication

No, fasting is not required

Antonije Lazic, PhD, MHA, is ACHIs director of research