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In response to growing concern surrounding delayed gastric emptying and aspiration risk, anesthesia societies and regulatory agencies have issued updated guidance addressing perioperative management of patients taking semaglutide and tirzepatide medications
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In non-diabetic mice, GLP-1 infusion increased GFR by reducing preglomerular resistance [20], an observation that could potentially explain the physiological increase in GFR observed in the postprandial compared to the fasting state, although human studies infusing GLP-1 peptide could not replicate this observation [21]
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