They can reduce hunger, improve satiety, and help patients achieve weight loss that may have been difficult to sustain through lifestyle changes alone
However, the decision will depend on several factors, such as: Personal health profile : Your overall health, pre-existing conditions, and current medications can determine whether it is right for you
Remarkably, the efficacy that we are seeing with regards to changes in body weight are approaching what we see with bariatric surgery, something we discussed in detail in a previous webinar Underneath the lost kilos: weight loss in metabolic disease
Per a 2021 analysis published in Diabetes Obesity Metabolism , nearly 50% of patients on semaglutide report nausea.41 Side effects tend to be dose dependent and may lessen in intensity with ongoing treatment.42,43 An underlying cause for these GI complaints relates to one of the ways in which GLP-1 medications work, which involves delayed gastric emptying
After all, carnitine supplements are sometimes part of a treatment regimen
In this context, GLP-1R agonists have been shown to affect the central nervous system and exhibit neuroprotective properties in animal models of several neurodegenerative diseases, including Alzheimers and Parkinsons disease, stroke, diabetic retinopathy, and ocular hypertension (McClean et al., 2011
