During the process of ferroptosis, the mitochondrial crest was decreased or disappeared, the membrane potential was changed, and the mitochondrial outer membrane was ruptured, and this led to mitochondrial function disruption
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Although there was a significant difference between the supplementation protocols in creatine levels, the same significant reductions in plasma Hcy concentrations were observed in both the DCr and CrO+D groups compared with the control group, with no changes in methionine concentration (Fig
doi: 10.2337/db23-56-OR 58 KillionEAChenMFalseyJRSivitsGHagerTAtanganLet al