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Combined administration of bezafibrate and the dipeptidyl peptidase-4 inhibitor des-fluoro-sitagliptin improved glucose tolerance, islet architecture and beta cell mass in db/db mice, whereas either compound alone had no effect

But many other factors affect results too, including diet , food choices , stress, sleep, and natural plateaus

Once opened or mixed, stability timelines vary based on the specific compound formulation, preservative system, and storage container