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The scores of all PANSS domains were significantly decreased after treatment ( P 0.05), while the BMI, waist circumference, TG, and VLDL were increased after treatment

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Independently of these peripheral actions, GLP-1RAs show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, bloodbrain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion