For patients with active cancer or recent cancer treatment, coordination with oncology specialists may be appropriate
seek immediate medical attention for severe abdominal pain, allergic reactions, or signs of pancreatitis
Set expectations Set realistic expectations regarding weight loss and menstrual cycle normalization
The Phase 2 clinical trial showed approximately 2-3 kg of additional fat loss compared to placebo over 12 weeks
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In this Review, we posit that eight molecular hallmarks are common denominators in cardiovascular ageing, namely disabled macroautophagy, loss of proteostasis, genomic instability (in particular, clonal haematopoiesis of indeterminate potential), epigenetic alterations, mitochondrial dysfunction, cell senescence, dysregulated neurohormonal signalling and inflammation