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Replacement of Tyr110 in recombinant Y110A decreased both k cat app and 1/ values for the disulfide substrate and GSH in the GSSCys and HEDS assay (Supplementary Figs 18 and 19)
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Older adults also show inflammatory markers like IL-6 are often much higher than in young adults, and chronically elevated inflammation is associated with heart disease, diabetes, and cognitive decline
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