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Both treatment groups also reported a significantly greater improvement in knee pain and physical function than the placebo group, as well as an improvement of cardiovascular risk factors, such as lower blood pressure

The positive impact on their lives extends beyond the physical aspect, contributing to increased energy, heightened motivation, and an overall improvement in their quality of life

The most common side effects are gastrointestinal and tend to improve after the first few weeks: Nausea, vomiting, or diarrhea (most common, especially early on) Constipation or stomach discomfort Reduced appetite Less common but serious side effects include pancreatitis, gallbladder issues, and low blood sugar particularly in patients taking diabetes medications

For example, a patient who does not have insurance coverage may be better suited for phentermine, which is relatively inexpensive

Place hands slightly wider than shoulders

doi: 10.1016/j.psychres.2021.113841 52 ZhaiZGuoY