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CagriSema (cagrilintide + semaglutide) has Phase 3 trial data but uses a weaker incretin backbone (just GLP-1)

A single subcutaneous dose elevated serum IGF-1 for more than six days in healthy adults (Teichman et al., 2006)

If you do experience side effects, they usually subside after a few weeks of your body getting used to the medication

This isnt bleaching or altering skin structure

Hypoglycemia When used as monotherapy or with medications that do not cause hypoglycemia, semaglutide carries very low risk of low blood sugar because its insulin-stimulating effects are glucose-dependent