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The main reason is the lack of human studies
After an extensive process of reviewing studies, engaging in public debate and processing feedback, ICER concluded that semaglutide for weight loss should have an annual cost of $7,500 to $9,800, based on its potential benefits
As the current guidelines have made this recommendation, other organizations and authors have also advocated for the use of these imaging techniques due to their relatively inexpensive and effective nature (Oprea et al
doi:10.1016/j.chom.2014.03.012 178
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