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The medication has a half-life of approximately seven days, which allows for once-weekly dosing and contributes to stable blood levels throughout the week
For example, use the upper-outer region one week, middle-outer region the next, and lower-outer region the following week, then repeat the cycle
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Biomedicines 10 , 1020 (2022)
McConnell added, "Not knowing the safety of the drug, I think [patients] should be cautious and try not to get pregnant while taking it because we don't know the long-term effects." Both doctors recommended the use of "backup barriers," or extra contraceptives, while taking GLP-1 drugs
Furthermore, blockade of the IL-6 receptor with tocilizumab reduces meal-stimulated levels of GLP-1 in people with type 2 diabetes or obesity [129]
