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Unlike single- or dual-receptor peptides, Retatrutide simultaneously targets three key metabolic receptors: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

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Toptas, B., Baykal, A., Yesilipek, A., Isbir, M., Kupesiz, A., Yalcin, O., and Baskurt, O