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Intravenous acetylcysteine (Parvolex/Acetadote) is used as a continuous intravenous infusion over 20 hours (total dose 300 mg/kg)
J Macromol Sci Part C 58(3):537586 Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy AN, Miyamoto S, Guma M (2018) Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis
This bilirubin is initially unconjugated and must undergo a series of well-orchestrated steps involving hepatic uptake, enzymatic conjugation, and biliary excretion before it is ultimately eliminated from the body
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Together, the three actives work through complementary pathways rather than a single mechanism
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