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DOI: 10.1186/s12970-014-0059-0 Fasano A
These findings are consistent with broader nanotoxicology literature, including ferric oxide nanoparticle studies, which emphasize macrophage sequestration, oxidative stress markers, and organ-specific histopathology as key endpoints for safety assessment ( Doseresponse trends underscore the dual nature of AgNPs as both therapeutic and potentially toxic agents
Tissue samples from lean and ob/ob mice were homogenized in TRIzol reagent, followed by RNA extraction using standard protocols
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Add 1 mL of Reagent I (the proportion of tissue and reagents can be kept constant), fully grinding on ice (using liquid nitrogen will have a better grinding effect)
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