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The study found that NNMT inhibitors "reduced intracellular 1-MNA, increased intracellular NAD+ and S-(5-adenosyl)-L-methionine (SAM), and suppressed lipogenesis." This metabolic improvement occurs within days of starting treatment, before any weight loss becomes measurable
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Researchers achieve the best results when the compound supplements rather than substitutes for appropriate diet and exercise
Presented for research literature review only Katada T et al
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