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Farnesyltransferase is an enzyme for farnesylation on the cysteine residue of the CAAX motif region of cytosolic RAS protein, resulting in RAS protein association with cellular membranes
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33.4 pM for GIP) but approximately 13-fold weaker potency than GLP-1 in activating GLP-1R (EC50 = 934 pM for tirzepatide vs.70.5 pM for GLP-1)
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A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol
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Microbial imbalances can also impact the tumor microenvironment, promoting tumorigenesis (Wang et al., 2023)
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