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Neurological issues like reduced muscle tone (hypotonia), body temperature instability, and seizures

28 days) hydrochloride improves cognitive function in the cognitive impairment model of aged rats, enhances synaptic plasticity in the hippocampus, and increases the expression of brain-derived neurotrophic factor (BDNF) [3]

Its a good choice for the gut health benefits this supplement is designed to impart, as a pair of randomized, double-blind, and placebo-controlled trials in 2019 found that a 10g daily dose of the stuff significantly improved stool frequency in a cohort at increased risk for constipation (ages 4075).29 Other studies, including a 2024 systematic review and meta-analysis, determined that chicory inulin may even help with weight management.30 The issue is that successful studies have used very high doses at least 10g per day, as opposed to the 276mg in Akkermansia so the chicorys role here appears to be exclusively as a food for the bacterial species

If you weigh 90kg and stand 1.75m tall, that is 90 divided by (1.75 times 1.75), which equals 90 divided by 3.0625, which equals 29.4

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The Role of GLP-1 in Appetite Regulation The first major player is a hormone called glucagon-like peptide-1 (GLP-1)