The medication requires ongoing use to maintain weight loss, as demonstrated in the SURMOUNT-4 trial, where discontinuation led to weight regain
What STEP-1 Showed: Semaglutide's Impact on Lean Mass In the STEP-1 trial, participants on semaglutide 2.4 mg per week lost approximately 15% of total body weight over 68 weeks
For better recovery and reduced muscle damage post-exercise take it in your post-workout shake or meal
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In practical terms, that means it helps drive appetite suppression, improved satiety, slowed gastric emptying, and broader metabolic effects that go beyond what older single-pathway GLP-1 compounds were able to do
Semaglutide can be used in people with most heart, kidney, liver, and endocrine conditions