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What they did: Obese mice received AOD-9604 orally (via gavage) for 14 days at various doses (50, 250, 500 g/kg)
The bottom line re Metformin Metformin shows promise for extending healthspan by preventing diseases like diabetes, heart disease, and dementia
By the way, even if you dont have pernicious anemia, but a severe B12 deficiency due to other causes, B12 shots are still the way to go
The BV-2 cell line, representing microglia, serves as a well-established in vitro model for studying microglia-induced neuroinflammation 43
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This suggests the reliability of GSH_cs MD stable conformation
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