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Highlights of prescribing information: Wegovy (semaglutide) injection, for subcutaneous use

40 Nevertheless, accumulating evidence indicates that CR is detrimental to skeletal metabolism, as evidenced by reductions in BMD and bone mineral content (BMC), diminished bone formation indices (e.g., bone formation rate, osteoblast number), and a concomitant increase in bone resorption

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No Validated Epithalon Age-Reversal Test Commercial testing before and after Epithalon exposure cannot establish rejuvenation unless the test is validated, the change exceeds normal variation and a controlled comparator is included

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Key cited studies: Maquart FX et al