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Chinese herb related molecules catechins, caudatin and cucurbitacin-I inhibit the proliferation of glioblastoma by activating KDELR2-mediated endoplasmic reticulum stress
Supporting this epidemiologic signal, large cohort data also suggest an inverse relationship between GLP-1 exposure and a core pathological hallmark of Alzheimers disease: the accumulation of amyloid in the brain [32].While observational data cannot establish causality, the convergence of reduced clinical incidence and favorable biomarker associations strengthens the case that GLP-1 signaling may be influencing disease-relevant biology rather than serving as a passive metabolic proxy
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NICE guidelines (NG136, NG28) recommend individualised blood pressure targets, typically below 140/90 mmHg for most people with diabetes, or below 130/80 mmHg if you have kidney, eye, or cerebrovascular disease
[7] It is well established that low muscle mass and muscle strength are associated with a higher risk of all-cause mortality and disability
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