doi: 10.1038/leu.2014.41 104 QinBWangJYangZYangMMaNHuangFet al
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These wide-ranging effects explain why glutathione depletion has been associated with accelerated aging, increased disease susceptibility, impaired detoxification capacity, and compromised immune responses
VEGFR2 activation Akt phosphorylation induction of endothelial nitric oxide synthase (eNOS) NO release local vasodilation and formation of new blood vessels at the injury site
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These findings may be relevant to human disease