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It also depletes the very micronutrients described above: chronic cortisol elevation increases urinary magnesium excretion, a mechanism well-documented in the stress-physiology literature, compounding the deficiency burden already present in obesity

5 BatlaA.SimeoniS.UchiyamaT.deMinL.BaldwinJ.MelbourneC.et al (2021)

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While both drugs have shown efficacy in promoting weight loss, Semaglutide emerges as a superior choice due to its unique mechanism of action and overall effectiveness