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More rigorous studies with a prospective design will help to characterize the potential beneficial effects of semaglutide on food noise reduction, and how this is related to clinical improvements such as weight loss
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Give any protocol change at least 4 to 6 weeks before evaluating
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Colonic biopsies from these patients also show reduced GLP-1R expression, suggesting that decreased GLP-1 and GLP-1R expression may underlie the efficacy of ROSE-010 in alleviating IBS-C abdominal pain [61]
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