Gap junction dysfunction reduces acetaminophen hepatotoxicity with impact on apoptotic signaling and connexin 43 protein induction in rat
Furthermore, increased ACE2 expression in alveolar type II pneumocytes and alveolar macrophages of individuals with severe SARS-CoV-2 disease (ARDS with diffuse alveolar damage) requiring mechanical ventilation (Baker et al., 2021) favors a concomitant increase in oxidative stress in those individuals
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We observed that at early stages of tumour progression, NKX2-1 functions as a tumor suppressor, but later becomes an aggressive oncogene , contributing to cancer progression when nutrients such as serine and glycine become scarce
Chang Y, Wei W, Zhang L, Xu HM