Development was discontinued because the Phase IIb trial of 536 subjects over 24 weeks failed to meet its primary efficacy endpoint
In addition to supplementation for deficiency, methylcobalamin has been studied for its potential role in sleep regulation and mood support, but findings remain preliminary
The problem is not limited to the elderly
The body absorbs only as much B12 as it needs, and any excess is eliminated naturally
It also aids in normal cell division, red blood cell production, nervous function, immune system health, reducing tiredness and fatigue, and more
Showing a family the STEP TEENS forest plot, with BMI reductions of 16.1% in adolescents treated with semaglutide versus essentially zero with placebo, gives them a concrete comparator [11]