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Its still widely used today
In patients with pre-existing inflammatory bowel disease (IBD), these effects may blur with disease activity, making it harder to distinguish between medication side effects and ulcerative colitis flares
A specific gut microbiota dysbiosis of type 2 diabetic mice induces GLP-1 resistance through an enteric NO-dependent and gut-brain axis mechanism Cell Metabolism2017;25(5):1075-1090
It can, however, be injected at a "deep subcutaneous" level, which is essentially the border between cutaneous and muscular
Presented for research literature review only Kraus P et al
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