eLife 8, e50208
Complete supply calculation for a 16-week protocol Weeks 1-4 (2mg/week): 2mg x 4 weeks = 8mg total Weeks 5-8 (4mg/week): 4mg x 4 weeks = 16mg total Weeks 9-12 (8mg/week): 8mg x 4 weeks = 32mg total Weeks 13-16 (12mg/week): 12mg x 4 weeks = 48mg total Grand total: 104mg over 16 weeks Now translate that into vials: Using 10mg vials exclusively: 104mg / 10mg = 10.4 vials
Swiss Med Wkly 2004;134:385
Duffy DL, Montgomery GW, Chen W, Zhao ZZ, Le L, James MR, Hayward NK, Martin NG, Sturm RA
Retatrutide is administered as a once-weekly subcutaneous injection , based on the dosing schedule used in Phase 2 trials
Via the incretin pathway, they stimulate insulin release, suppress glucagon release, slow down gastric emptying, and enhance central satiety signal