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A number of other studies have also suggested that chronic stress causes atrophy of the PFC and hippocampus owing to glucocorticoid imbalance (McEwen et al., 2012)

doi:10.1002/lio2.338

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The findings were independent of overweight/obesity category at baseline, as seen in this subgroup analysis for the primary endpoint

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Similarly, Novo Nordisk makes both insulin degludec (Tresiba) and semaglutide (Ozempic), plus a combination product called Xultophy that pairs insulin degludec with liraglutide