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Wegovy contains semaglutide for chronic weight management, while Ozempic is approved for type 2 diabetes and related indications
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By activating GLP-1 receptors, semaglutide stimulates insulin secretion, reduces the production of glucagon (a hormone that raises blood sugar levels), slows down stomach emptying, and promotes feelings of fullness [2]
Your optimal calorie intake while on semaglutide should create a moderate calorie deficittypically 500 to 750 calories below your total daily energy expenditureto promote steady, sustainable weight loss of approximately 1 to 2 pounds per week
Weeks 4 to 12 This is where the results become visible
ADA/EASD consensus reports have even proposed GLP-1 RAs as first-line injectable therapy before insulin for most T2D patients who need an injection, given the superior weight and hypoglycemia profile
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