Puerarin ameliorates depression-like behaviors of with chronic unpredictable mild stress mice by remodeling their gut microbiota
He did so by identifying spontaneous mutations in the gene coding for mouse Toll-like receptor 4 ( Tlr4 ) in two unrelated strains of LPS-refractory mice and proving they were responsible for that phenotype
Endocrinology 141 , 111117 (2000)
They say the peptide, which has already been tested in Europe in patients with acute lung injury, like pneumonia or trauma, and is being pursued in lung transplant patients as well, holds promise for a targeted therapy for acute nephritis
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