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The liver cytosol model is rich in phase II metabolic enzymes, which can simulate liver metabolism more completely when combined with liver microsomes

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(PubMed) Estrada DE, Ewart HS, Tsakiridis T, et al

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The strength of the findings in this report is enhanced due to the scale and duration of the study including 21 expert authors, the 800 centers, 17,000 subjects and the duration of 2 years, 2