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Moreover, pharmacological or genetic inhibition of inflammatory signaling in preclinical models of obesity prevents high-fat diet (HFD)-induced glucose intolerance and insulin resistance [79]

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Each individual fast food restaurant is going to figure out how to take [that] share away from others. Haracz said that restaurants were more likely to prioritize getting customers through the door, even if that meant they were ordering less food and smaller portions, than lose them completely

et al: Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

However, acetylation patterns vary by cell type, histone residue, and stress paradigm, and the therapeutic specificity of HDAC inhibitors remains an important challenge for clinical translation

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