Evolution in an ancient detoxification pathway is coupled with a transition to herbivory in the drosophilidae
Tirzepatide is a dual agonist, acting on both GLP-1 and GIP receptors, which is why clinical trials showed stronger average weight loss outcomes for tirzepatide
Participants who reported food tasting sweeter after taking GLP-1s were twice as likely to report increased satiety, 67% more likely to report a reduction in appetite, and 85% more likely to report a reduction in food cravings
The potential main mechanism responsible for SGLT2-i reno-protective properties probably resides in TGF activation and glomerular hyperfiltration reduction
For severe symptoms such as persistent vomiting, signs of dehydration, severe abdominal pain, or sudden vision changes, seek urgent medical review or call 999
Gastroparesis and broader gastrointestinal dysmotility are already very common in EDS